WARNING: Do not use ISOTANE if you are pregnant. Do not become pregnant during use, or within one month of stopping treatment with ISOTANE. MAJOR RISK OF BIRTH DEFECTS. Effective birth control must be used. Keep out of reach of children.
There are several contributing factors to acne:There are several contributing factors to acne:
increased sebum production, and
changes within the hair follicle.
During puberty or adolescence there is an increase in the production of sex hormones (mainly androgens and testosterone). This causes the sebaceous glands to produce increased amounts of sebum. Also during puberty, the skin cells lining the hair follicle shed at a faster rate, increasing the probability that the sebum and skin cells present will stick together and result in blockage of the hair follicle.
The number of bacteria on the skin surface also increases during puberty.
Young men are more likely to have severe, longer lasting acne than women due to higher levels of testosterone. Young women are prone to cycles of acne due to hormonal changes that occur during their menstrual cycle.
Other factors that may contribute to acne include:
use of greasy or oily cosmetics
a family history of acne
use of certain medicines such as glucocorticoids, iodides, lithium, bromides or anticonvulsants;
abrasion caused by over-vigorous scrubbing; frequent shaving or other manipulation to the skin;
exposure to airborne pollutants;
exposure to high heat and humidity.
Isotane (isotretinoin) 10 mg, 20mg Capsules are a Prescription Medicine used to treat severe forms of acne that are resistant to other treatments. WARNING: This medication can cause birth defects. Do not use if you are pregnant or plan to become pregnant. Effective birth control must be used
one month before starting Isotane treatment, during treatment and for at least one month after treatment has finished. Do not take if you have an
allergy to isotretinoin, other retinoids including vitamin A or any of the excipients; are pregnant or intend to become pregnant; are breastfeeding; have
kidney or liver disease; have an excessive amount of vitamin A in your diet; are taking tetracycline antibiotics; have very high levels of fat (triglycerides,
cholesterol) in your blood. Tell your doctor if you are depressed or have felt this way in the past; if you have thoughts about harming yourself; drink
large amounts of alcohol; are taking the mini-pill; intend to undertake regular vigorous exercise or have any other health problems. Side effects include
dryness of the lips, mouth, throat, nose, eyes, genitals or skin; skin eruptions, rashes, redness, sweating; nail inflammation, infection or altered appearance;
nosebleeds; tenderness, soreness or stiffness in your bones, joints or muscles; impaired hearing; headache; increased sensitivity to sunlight; hair
loss, thinning or increased growth; changes in normal behaviour; blurred vision, decreased night vision; nausea, vomiting, diarrhoea. Medicines have
benefits and some may have risks. Consult your doctor to see if Isotane is right for you. Always read the label carefully and use strictly as directed. If
symptoms persist or you have side effects, see your health professional. Full Consumer Medicine Information (CMI) is available at www.medsafe.govt.
nz. Isotane is fully funded on special authority. Normal doctor’s fees & pharmacy charges apply.Mylan NZ Ltd., Auckland. TAPS NA7865